(Educational, Non-Commercial use only!)
Sorry for no actual values on components. This circuit is untested.
I won't do too much explaining, you can either read it, or you can't.
If you notice a screw-up though, please tell me.

My project will have four indicator lights/buttons on the front of the box.
http://www.zapwizard.com/Projects/wood/version3/11.jpg
POWER - DVD - IDE - WIFI
The buttons are touch-sensative via a QTouch IC (www.qprox.com)
The output of the QProx is connected to an opto-isolator, as the Qtouch IC is sensative to voltage spikes and power loads. The QTouch is powered off +5volts standby
The output of the Opto drives four relays which are connected to the Matrix Obital keypad input.
The opto output is also hardwired to drive Motherboard power on, and DVD EJect. Windows can be programed to control what it does when you press power.
There are four tiny lights above the buttons that are more for decoration then anything. But through some diode trickery, they will be wired so that when you press the button below, the LED above turns off, providing tactic feedback.
All the front panel LEDs can be driven by a High Power Output on the Matrix Orbital, allowing for dimming, without loosing functionality. There is also a jumper for pure +12volts.
There are four input LED signals, these allow for connection of Power, IDE activity, DVD Activity, and WIFI Activity signals. These inputs drive an Opto directly to isolate them from the circuit. The four indicator LEDs will be used to back-light the buttons, and will remain on when the input signal is inactive. (Inverted) This is done by shorting the LEDs out via the Opto's transitors. An additional resistor will ensure that when active the LEDs will not turn 100% off, but will rather flicker and dim when active.
In the final build I may install jumpers that will allow either the back-lit button LEDs, and the small point lights to be swapped.